Liquid recirculation in microfluidic channels by the interplay of capillary and centrifugal forces
Garcia-Cordero, Jose L., Basabe-Desmonts, Lourdes, Ducrée, JensORCID: 0000-0002-0366-1897, Lee, Luke P. and Ricco, Antonio J.
(2009)
Liquid recirculation in microfluidic channels by the interplay of capillary and centrifugal forces.
In: TRANSDUCERS 2009 - International Solid-State Sensors, Actuators and Microsystems Conference, 21-25 June 2009, Denver, USA.
ISBN 978-1-4244-4193-8
We demonstrate a technique to recirculate liquids in a microfluidic device, maintaining a thin fluid layer such that typical diffusion times for analytes to reach the device surface are < 1 min. Fluids can be recirculated at least 1000 times across the same surface region, with no change other than slight evaporation, by alternating the predominance of centrifugal and capillary forces. Mounted on a rotational platform, the device consists of two hydrophilic layers separated by a thin pressure-sensitive adhesive (PSA) layer that defines the microfluidic structure. We demonstrate rapid, effective fluid mixing with this device.
TRANSDUCERS 2009 - International Solid-State Sensors, Actuators and Microsystems Conference.
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Institute of Electrical and Electronics Engineers. ISBN 978-1-4244-4193-8