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TIR-based dynamic liquid-level and flow-rate sensing and its application on centrifugal microfluidic platforms

Hoffmann, J. and Riegger, L. and Mark, D. and von Stetten, F. and Zengerle, R. and Ducrée, Jens (2009) TIR-based dynamic liquid-level and flow-rate sensing and its application on centrifugal microfluidic platforms. In: MEMS 2009 - 22nd IEEE International Conference on Micro Electro Mechanical Systems, 25-29 January 2009 , Sorrento, Italy. ISBN 978-1-4244-2978-3

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Abstract

For the first time we present a technique for the spatio-temporally resolved localization of liquid-gas interfaces on centrifugal microfluidic platforms based on total internal reflection (TIR) at the channel wall. The simple setup consists of a line laser and a linear image sensor array mounted in a stationary instrument. Apart from identifying the presence of (usually unwanted) gas bubbles, the here described online meniscus detection allows to measure liquid volumes with a high precision of 1.9%. Additionally, flow rates and viscosities (range: 1-10.7 mPa s) can be sensed even during rotation at frequencies up to 30 Hz with a precision of 4.7% and 4.3%, respectively.

Item Type:Conference or Workshop Item (Paper)
Event Type:Conference
Refereed:Yes
Uncontrolled Keywords:flow measurement; level measurement; rotational flow;
Subjects:Biological Sciences > Microfluidics
DCU Faculties and Centres:Research Initiatives and Centres > Biomedical Diagnostics Institute (BDI)
Published in:Proceedings of the 22nd IEEE International Conference on Micro Electro Mechanical Systems. . Institute of Electrical and Electronics Engineers. ISBN 978-1-4244-2978-3
Publisher:Institute of Electrical and Electronics Engineers
Official URL:http://dx.doi.org/10.1109/MEMSYS.2009.4805438
Copyright Information:©2009 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
ID Code:15463
Deposited On:14 Jul 2010 14:34 by DORAS Administrator. Last Modified 14 Jul 2010 14:34

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