CMAS: fully integrated portable centrifugal microfluidic analysis system for on-site colorimetric analysis
Czugala, Monika and Maher, Damien and Collins, Fiachra and Burger, Robert and Hopfgartner, Frank and Yang, Yang and Zhou, Jiang and Ducrée, Jens and Smeaton, Alan F. and Fraser, Kevin J. and Benito-Lopez, Fernando and Diamond, Dermot (2013) CMAS: fully integrated portable centrifugal microfluidic analysis system for on-site colorimetric analysis. RSC Advances, 36 . pp. 15928-15938. ISSN 2046-2069
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A portable, wireless system capable of in-situ reagent-based colorimetric analysis is demonstrated. The system is based on a reconfigurable low cost optical detection method employing a paired emitter detector diode device, which allows a wide range of centrifugal microfluidic layouts to be implemented. Due to the wireless communication, acquisition parameters can be controlled remotely and results can be downloaded in distant locations and displayed in real time. The stand-alone capabilities of the system, combined with the portability and wireless communication, provide the flexibility crucial for on-site water monitoring.
The centrifugal microfluidic disc presented here is designed for nitrite detection in water samples, as a proof of principle. A limit of detection of 9.31 ppb, along with similar coefficient of correlation and precision, were obtained from the Centrifugal Microfluidic Analysis System compared with the same parameters measured using a UV-Vis spectrophotometer.
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