Automating the integration of clinical studies into medical ontologies
Roantree, Mark, O'Donoghue, Jim, O'Kelly, Noel, van Boxtel, Martin and Köhler, Sebastian
(2014)
Automating the integration of clinical studies into medical ontologies.
In: 47th Annual Hawaii International Conference on System Sciences (HICSS-47), 6-9 Jan 2014, Big Island, Hawaii.
A popular approach to knowledge extraction from clinical databases is to first define an ontology of the concepts one wishes to model and subsequently, use these concepts to test various hypotheses and make predictions about a person’s future health and wellbeing. The challenge for medical experts is in the time taken to map between their concepts/hypotheses and information contained within clinical studies. Presently, most of this work is performed manually. We have developed a method to generate links between Risk Factors in a medical ontology and the questions and result data in longitudinal studies. This can then be exploited to express complex queries based on domain concepts, to extract knowledge from external studies.