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Xurography actuated valving for arbitrary timing of centrifugal flow control in parallelized multi-step bioassays

Kinahan, David J. and Vembadi, Abhishek and MacNamara, Eoghan and Kilcawley, Niamh and Early, Philip and Glennon, Tom and Diamond, Dermot and Brabazon, Dermot and Ducrée, Jens (2015) Xurography actuated valving for arbitrary timing of centrifugal flow control in parallelized multi-step bioassays. In: The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2015), 25-29 Nov 2015, Gyeongju, Korea.

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Abstract

Here we introduce a new, instrument controlled valving scheme for the centrifugal platform which is based upon dissolvable film (DF) technology. Liquid, restrained at any point upon the disc, is prevented from wetting a DF via a trapped gas pocket. From this pocket a pneumatic channel runs to a sealed vent located on the top surface of the disc. Controlled scouring of this seal by a robotic knifecutter permits venting of the trapped gas, and thus actuation of the valve. To demonstrate the potential of these valves, we present a disc developed towards a biplex liver assay panel.

Item Type:Conference or Workshop Item (Poster)
Event Type:Conference
Refereed:Yes
Uncontrolled Keywords:Xurography; Centrifugal Microfluidics; Dissolvable Films
Subjects:UNSPECIFIED
DCU Faculties and Centres:Research Initiatives and Centres > Biomedical Diagnostics Institute (BDI)
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
ID Code:20974
Deposited On:26 Jan 2016 11:43 by David Kinahan. Last Modified 19 Dec 2016 10:05

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