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Next generation PCR microfluidic system

Morris, Angela, Curtin, Damian, McGuire, David, Witherbee, Bryan, Barrett, Brian, Kinahan, David J. orcid logoORCID: 0000-0003-1968-2016, Sayers, Michael, Sirr, Noel, Hou, Xiaona, Aguanno, Mauro, King, Damien, McCarthy, Conor, Chawke, Brian, Doolan, David, O'Doherty, Sinead, Walsh, Jim, Curran, Kieran, Davies, Mark, Dalton, Tara, Bauer, Chris and Le, Thomas (2010) Next generation PCR microfluidic system. In: Lab on a Chip European Congress 2010, 25-26 May 2010, Dublin, Ireland.

Stokes Bio, founded in 2005, develops innovative microfluidic technologies. In 2008 in collaboration with Monsanto, an application driven development for a high-throughput instrument in the detection and characterisation of Single Nucleotide Polymorphisms (SNPs) in agricultural crops was initiated. Stokes technology is designed to generate aqueous nanolitre scale droplets of reagents and samples, wrapped in a carrier fluid from standard microtitre plates and to mix them using Stokes Bio’s proprietary liquid bridge mixers. Following mixing the complete assay is transferred in the carrier fluid through the use of a continuous flow system, to a flow through thermal cycler and an optical reading station. This poster summarises results collated using the Stokes Bio genotyping platform currently based in Monsanto. Data will be presented to illustrate the dynamic capabilities of the instrument, highlighting the enhanced sensitivity and reproducibility of PCR in droplet format compared to well-based technologies.
Item Type:Conference or Workshop Item (Poster)
Event Type:Conference
Subjects:Engineering > Biomedical engineering
DCU Faculties and Centres:Research Institutes and Centres > Biomedical Diagnostics Institute (BDI)
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
ID Code:20453
Deposited On:27 Feb 2015 09:18 by David Kinahan . Last Modified 26 Oct 2018 10:01

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