Lumped element simulation of a highly integrated bioanalytical centrifugal processing unit (“BioCPU”)
Mohammadi, Mahdi, Kinahan, David J.ORCID: 0000-0003-1968-2016 and Ducrée, JensORCID: 0000-0002-0366-1897
(2016)
Lumped element simulation of a highly integrated bioanalytical centrifugal processing unit (“BioCPU”).
In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences 9-13 October, 2016, Dublin, Ireland, 9-13 Oct 2016, Dublin, Ireland.
ISBN 978-0-9798064-9-0
The centrifugal microfluidic platforms have evolved into a mature technology for a broad range of applications, for example in the life sciences, biomedical point-of-care diagnostics, and environmental monitoring. Whilst considerable progress has been made on functional elements of the Lab-on-a-Disc (LoaD) platform, the design of complex, highly integrated networks representing sample-to-answer automation of multi-step biochemical assays remains a significant challenge. This paper addresses a developed microfluidic simulation tool for the efficient layout, simulation and analysis of high performance LoaD systems implemented by featuring a novel, “digital” flow control scheme.