Evaluation of trends in a series of halogenated isophthalamides
Gallagher, JohnORCID: 0000-0003-4130-4556 and Osman, Islam Ali
(2019)
Evaluation of trends in a series of halogenated isophthalamides.
In: 32nd European Crystallographic Meeting ECM32, 18-23Aug 2019, Vienna.
The effect of halogens (X) and the pyridine N atom substitution patterns on molecular structure and conformation in a series of isophthalimides is analyzed. The work is based on previous and on-going research on isomer grids of halogenated benzamides. The analysis integrates crystal structure analyses, computational chemistry and conformational analyses together with NMR data and melting point data. The study highlights the structural systematics survey of several halogenated isophthalimides (X-DIPs) as represented by 1 (Scheme; Figures) with only the salient features of the conformations presented herein.