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Hydrophilic polymeric coatings for enhanced, serial-siphon based flow control on centrifugal lab-on-disc platforms

Kitsara, Maria and Nwankire, Charles and O'Reilly, Adrian and Siegrist, Jonathan and Donohoe, Gerard G. and Zhang, Xin and O'Kennedy, Richard and Ducree, Jens (2012) Hydrophilic polymeric coatings for enhanced, serial-siphon based flow control on centrifugal lab-on-disc platforms. In: μTAS 2012, 28 Oct - 1 Nov 2012, Okinawa, Japan.

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Abstract

In this paper, we implement rotational flow control on a polymeric microfluidic “lab-on-a-disc” device by combining serial siphoning and capillary valving for sequential release of on-board stored liquid reagents. The functionality of this integrated, multi-step centrifugal assay platform is tightly linked by the capability to establish reproducible, capillary-driven priming of the innately hydrophobic siphon microchannels. We here demonstrate for the first time that spin-coated hydrophilic polymeric films of poly(vinyl alcohol) and (hydroxylpropyl)methylcellulose provide stable contact angles.

Item Type:Conference or Workshop Item (Paper)
Event Type:Conference
Refereed:Yes
Uncontrolled Keywords:Hydrophilization; spin coating; centrifugal microfluidic platform; lab-on-a-disc; capillary force; serial siphon
Subjects:UNSPECIFIED
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Physical Sciences
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
ID Code:17178
Deposited On:31 Oct 2012 14:57 by Fran Callaghan. Last Modified 31 Oct 2012 14:57

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