Hydrophilic polymeric coatings for enhanced, serial-siphon based flow control on centrifugal lab-on-disc platforms
Kitsara, Maria and Nwankire, Charles and O'Reilly, Adrian and Siegrist, Jonathan and Donohoe, Gerard Gary and Zhang, Xin and O'Kennedy, Richard and Ducrée, Jens (2012) Hydrophilic polymeric coatings for enhanced, serial-siphon based flow control on centrifugal lab-on-disc platforms. In: μTAS 2012, 28 Oct - 1 Nov 2012, Okinawa, Japan.
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In this paper, we implement rotational flow control on a polymeric microfluidic “lab-on-a-disc” device by
combining serial siphoning and capillary valving for sequential release of on-board stored liquid reagents. The
functionality of this integrated, multi-step centrifugal assay platform is tightly linked by the capability to establish reproducible, capillary-driven priming of the innately hydrophobic siphon microchannels. We here demonstrate for the first time that spin-coated hydrophilic polymeric films of poly(vinyl alcohol) and (hydroxylpropyl)methylcellulose provide stable contact angles.
|Item Type:||Conference or Workshop Item (Paper)|
|Uncontrolled Keywords:||Hydrophilization; spin coating; centrifugal microfluidic platform; lab-on-a-disc; capillary force; serial siphon|
|DCU Faculties and Centres:||DCU Faculties and Schools > Faculty of Science and Health > School of Physical Sciences|
|Use License:||This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License|
|Deposited On:||31 Oct 2012 14:57 by Fran Callaghan. Last Modified 19 Dec 2016 10:17|
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