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High strength bioinspired calcium phosphate-based material for bone repair applications

Mussatto, Andre ORCID: 0000-0001-5335-7968, Doğu, Merve Nur ORCID: 0000-0003-1843-6040, Vijayaraghavan, Rajani K. ORCID: 0000-0003-1096-448X, Groarke, Robert, Obeidi, Muhannad A. ORCID: 0000-0003-2733-3828 and McGuinness, Garrett ORCID: 0000-0002-1023-8667 (2022) High strength bioinspired calcium phosphate-based material for bone repair applications. Materials Today Communications, 33 . ISSN 2352-4928

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Abstract

Owing to the increasing demand for bone repair strategies, several biomaterials have been developed. Among the materials available for this purpose, hydroxyapatite stands out for its osteoinduction capacity, since it possesses a chemical composition similar to that of inorganic bone constituents. In comparison to bones, the mechanical properties of substitute structures incorporating hydroxyapatite still remain a great challenge for scientists. This study thus presents the synthesis of hydroxyapatite incorporated with a natural bioceramic and a metallic phase of excellent biocompatibility to obtain dense biomaterials with improved mechanical strength. The mechanical responses of the synthesized biomaterials are presented and discussed. The results obtained indicate that the hydroxyapatite-natural ceramic systems fulfils the general mechanical property requirements for some bone repair applications. Separately, the synthesis of titanium-based systems was shown to be much more challenging, but promising. Therefore, recommendations for suppressing the issues with the metal-ceramic interfacial bonding strength were provided.

Item Type:Article (Published)
Refereed:Yes
Additional Information:Article number: 104693
Uncontrolled Keywords:hydroxyapatite; seashell; biocompatible material; biomedical applications; sustainability
Subjects:Engineering > Materials
Engineering > Mechanical engineering
Engineering > Biomedical engineering
Medical Sciences > Biomechanics
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Engineering and Computing > School of Electronic Engineering
DCU Faculties and Schools > Faculty of Engineering and Computing > School of Mechanical and Manufacturing Engineering
Publisher:Elsevier
Official URL:https://doi.org/10.1016/j.mtcomm.2022.104693
Copyright Information:© 2022 Elsevier
Funders:Science Foundation Ireland (SFI) under Grant Number 16/RC/3872 and co-funded under the European Regional Development Fund, School of Mechanical and Manufacturing Engineering in Dublin City University
ID Code:27876
Deposited On:21 Oct 2022 09:35 by André Mussatto . Last Modified 10 Jan 2023 13:58

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