With the ever growing complexity of high-frequency systems in the electronic industry, formation of reduced-order models or compact macromodels of these systems is paramount. In this contribution, a Fourier series expansion technique is extended to form a modeling strategy to approximate the frequency-domain behaviour of a system based on several design variables. In particular, it is intended to provide a tool for the designer to identify the effect of manufacturer tolerances and process fluctuations or irregularities on system behaviour.