The integration of sensors within wireless networks represents a pivotal step for remote analytical monitoring, not limited to pollutants in the environment but also suitable for diagnostics and personal health monitoring. For instance, higher spatial and temporal resolutions for toxic metals are fundamental for epidemiology studies, where they would help to establish definitive associations between the exposure to specific chemicals and the health of individuals and communities. In addition, accessible body fluids such as saliva and sweat represent an interesting medium for the realization of wearable sensors. These fluids contain important personalized physiological information. For example, a continuous monitoring of pH in saliva and electrolyte concentrations in sweat would be beneficial for controlling healthy mouth conditions or to improve endurance performances and avoid critical situations, e.g., dehydration and hyponatremia in athletes. Low-cost potentiometric strips based on screen printed substrates consisting of a solid-contact ion-selective electrode (SC-ISE) combined to a solid-contact reference electrode (SC-RE) may offer a versatile tool in sensing technology. These strips can be readily adapted for the detection of several ionic species. Here, as an example, we present on the monitoring of pH in saliva, Na+ in sweat and Pb2+ in water. The strip is plugged into an electronic platform of reduced dimensions which converts the chemical information into an electric signal, wireless transmitted to a base station. This technology may have an impact in remote monitoring but also in wearable sensing thanks to the device miniaturization.