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Advances in three-dimensional rapid prototyping of microfluidic devices for biological applications

O'Neill, Paul F. orcid logoORCID: 0000-0002-5374-034X, Ben Azouz, Aymen, Vázquez, Mercedes orcid logoORCID: 0000-0002-9770-5562, Liu, Jinghang, Marczak, Steven, Slouka, Zdenek, Chang, Hsueh Chia, Diamond, Dermot orcid logoORCID: 0000-0003-2944-4839 and Brabazon, Dermot orcid logoORCID: 0000-0003-3214-6381 (2014) Advances in three-dimensional rapid prototyping of microfluidic devices for biological applications. Biomicrofluidics, 8 (052112). ISSN 1932-1058

The capability of 3D printing technologies for direct production of complex 3D structures in a single step has recently attracted an ever increasing interest within the field of microfluidics. Recently, ultrafast lasers have also allowed developing new methods for production of internal microfluidic channels within the bulk of glass and polymer materials by direct internal 3D laser writing. This review critically summarizes the latest advances in the production of microfluidic 3D structures by using 3D printing technologies and direct internal 3D laser writing fabrication methods. Current applications of these rapid prototyped microfluidic platforms in biology will be also discussed. These include imaging of cells and living organisms, electrochemical detection of viruses and neurotransmitters, and studies in drug transport and induced-release of adenosine triphosphate from erythrocytes.
Item Type:Article (Published)
Subjects:Engineering > Materials
Engineering > Production engineering
Engineering > Mechanical engineering
Biological Sciences > Microfluidics
Biological Sciences > Cell biology
Medical Sciences > Biomechanics
Engineering > Biomedical engineering
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Engineering and Computing > School of Mechanical and Manufacturing Engineering
Publisher:AIP Publishing LLC
Official URL:http://dx.doi.org/10.1063/1.4898632
Copyright Information:© 2014 AIP
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:Science Foundation Ireland, Naughton Foundation
ID Code:20301
Deposited On:11 Nov 2014 11:02 by Paul Francis O Neill . Last Modified 04 Dec 2018 16:21


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