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Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus

Downing, Tim (2009) Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus. BMC Evolutionary Biology, 9 (136). ISSN 1471-2148

The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes involved in the chicken immune system are subject to particularly strong adaptive pressure. Signatures of selection detected by inter-species comparison may then be investigated at the population level in global chicken populations to highlight potentially relevant functional polymorphisms.
Item Type:Article (Published)
Uncontrolled Keywords:Genome sequencing
Subjects:Biological Sciences > Bioinformatics
Biological Sciences > Genetics
Biological Sciences > Immunology
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Biotechnology
Publisher:BioMed Central
Official URL:http://dx.doi.org/10.1186/1471-2148-9-136
Copyright Information:© 2009 BMC
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
ID Code:21043
Deposited On:27 Jan 2016 11:42 by Tim Downing . Last Modified 19 Jul 2018 15:07

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