The increased intracranial pressure (ICP) can be described as an increase in pressure around the brain and can lead to serious health problems. The assessment of ultrasound images is commonly conducted by skilled experts which is a time consuming approach, but advanced computer-aided diagnosis (CAD) systems can assist the physician to decrease the time of ICP diagnosis. The accurate detection of the nerve optic regions, with drawing a precise slope line behind the eyeball and calculating the diameter of nerve optic, are the main aims of this research. First, the Fuzzy C-mean (FCM) clustering is employed for segmenting the input CT screening images into the different parts. Second, a histogram equalization approach is usedforregion-basedimagequalityenhancement.Then,theLocalDirectionalNumbermethod(LDN)is used for representing some key information in a new image. Finally, a cascade Convolutional Neural Network (CNN) is employed for nerve optic segmentation by two distinct input images. Comprehensive experiments on the CT screening dataset [The Cancer Imaging Archive (TCIA)] consisting of 1600 images show the competitive results of inaccurate extraction of the brain features. Also, the indexes such as Dice, Specificity, and Precision for the proposed approach are reported 87.7%, 91.3%, and 90.1%, respectively. The final classification results show that the proposed approach effectively and accurately detects the nerve optic and its diameter in comparison with the other methods. Therefore, this method can be used for early diagnose of ICP and preventing the occurrence of serious health problems in patients.