Panagiotidis, Konstantino, Finegan, Grainne, Owens, Sally, Horgan, Noel, Tsavdaridis, Stefanos, Kennedy, Susan and Floudas, Achilleas (2025) Identification of two distinct uveal melanoma subtypes based on the immune cell infiltration of the primary tumour. Cancer Immunology, Immunotherapy, 74 (343). ISSN 1432-0851
Abstract
Our study reveals cellular and immunological heterogeneity within primary UM tumours. The identification of immunologically distinct tumour types, along with aggressive melanocyte subpopulations and stromal interactions, provides insight into UM pathogenesis and supports stratified immunotherapeutic approaches.
Metadata
| Item Type: | Article (Published) |
|---|---|
| Refereed: | Yes |
| Uncontrolled Keywords: | Uveal melanoma; T cells; RNAseq; Lymphoid; Myeloid |
| Subjects: | Engineering > Biomedical engineering Medical Sciences > Health Medical Sciences > Cancer |
| DCU Faculties and Centres: | DCU Faculties and Schools > Faculty of Science and Health DCU Faculties and Schools > Faculty of Science and Health > School of Biotechnology |
| Publisher: | Springer |
| Official URL: | https://link.springer.com/article/10.1007/s00262-0... |
| Copyright Information: | Authors |
| ID Code: | 31790 |
| Deposited On: | 05 Nov 2025 13:36 by Gordon Kennedy . Last Modified 05 Nov 2025 13:36 |
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