Lifelo, Zita, Ding, Jianguo, Wang, Zongjie, Shi, Feifei, Ning, Huansheng and Dhelim, Sahraoui
ORCID: 0000-0002-3620-1395
(2026)
Prompt-MAML: Model-Agnostic Meta-in-Context Learning for Major Depressive Disorder Classification.
Tsinghua Science and Technology
.
ISSN 1878-7606
Abstract
The classification of major depressive disorders (MDDs) is a challenging task in clinical practice, especially in low-resource scenarios where generalization is essential for effective adaptation. Recent progress in meta-training large language models (LLMs) via in-context learning (ICL) offers promise for robust adaptation to unseen tasks without parameter updates. However, existing methods rely on multitask fine-tuning and do not fully exploit the optimization advantages of model-agnostic meta learning (MAML) techniques, limiting their generalization. This study proposes prompt-MAML, a novel method for meta-training LLMs that enhances multimodal ICL for classifying MDD tasks. The method integrates audio-textual features through a transformer-based cross-modal alignment module and incorporates bi-level optimization to learn generalizable model parameters that adapt well to unseen tasks. Extensive experiments demonstrate that prompt-MAML outperforms strong baseline models by an average improvement in macro-F1 of +4 on seen domains, +3 on unseen domains, and +3 in few-shot settings, demonstrating robustness and effectiveness in data-scarce and cross-domain clinical scenarios. Additionally, exploration depth is shown to play a key role in task performance, and further analysis of task complexity, modality, and optimiser configurations highlights critical design considerations for meta-training LLMs.
Metadata
| Item Type: | Article (Published) |
|---|---|
| Refereed: | Yes |
| Uncontrolled Keywords: | large language model, multimodality, in-context learning, major depressive disorder detection, model-agnostic meta learning |
| Subjects: | Computer Science > Artificial intelligence Computer Science > Computational linguistics Computer Science > Machine learning Computer Science > World Wide Web |
| DCU Faculties and Centres: | DCU Faculties and Schools > Faculty of Engineering and Computing DCU Faculties and Schools > Faculty of Engineering and Computing > School of Computing |
| Publisher: | Qinghua Daxue Xuebao Bianjibu |
| Official URL: | https://www.sciopen.com/article/10.26599/TST.2025.... |
| Copyright Information: | Authors |
| ID Code: | 32442 |
| Deposited On: | 20 Mar 2026 15:18 by Sahraoui Dhelim . Last Modified 20 Mar 2026 15:18 |
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