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The phylogeny of the mammalian heme peroxidases and the evolution of their diverse functions

Loughran, Noeleen B., O'Connor, Brendan, Ó Fágáin, Ciarán and O'Connell, Mary J. (2008) The phylogeny of the mammalian heme peroxidases and the evolution of their diverse functions. BMC Evolutionary Biology, 8 . pp. 101-111. ISSN 1471-2148

The mammalian heme peroxidases (MHPs) are a medically important group of enzymes. Included in this group are myeloperoxidase, eosinophil peroxidase, lactoperoxidase, and thyroid peroxidase. These enzymes are associated with such diverse diseases as asthma, Alzheimer’s disease and inflammatory vascular disease. Despite much effort to elucidate a clearer understanding of the function of the 4 major groups of this multigene family, we still do not have a clear understanding of their relationships to each other.
Item Type:Article (Published)
Subjects:Biological Sciences > Bioinformatics
Biological Sciences > Biochemistry
Biological Sciences > Enzymology
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Biotechnology
Research Institutes and Centres > Irish Separation Science Cluster (ISSC)
Publisher:BioMed Central
Official URL:http://dx.doi.org/10.1186/1471-2148-8-101
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:Science Foundation Ireland, Enterprise Ireland
ID Code:17804
Deposited On:28 Feb 2013 14:07 by Brendan O'connor . Last Modified 19 Jul 2018 14:58

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