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Laser trapping microchip for biotechnological applications: design and development

Kolodziejczyk, Boleslaw Andrzej (2005) Laser trapping microchip for biotechnological applications: design and development. PhD thesis, Dublin City University.

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Abstract

This work presents a novel approach towards integrated dual-beam optical trapping achieved using planar lightwave circuit (PLC) technology. Three fabrication technologies sol-gel, photolithography and reactive ion etching were combined to fabricate a Laser Trapping Microchip (LTM) allowing one-dimensional manipulation of transparent micrometer-size spherical objects. Detailed steps of the LTM development are described, beginning with a theoretical approach and numerical simulations through the design and synthesis of a suitable photopatternable sol-gel material, culminating in the fabrication process and experimental confirmation of the trapping properties of the device. The proof of concept of this unique device was achieved by demonstrating its optical trapping abilities using micrometer size polystyrene beads with diameters in the range between 4 pm and 10 pm and the refractive index of 1 59. The LTM device possesses many advantages over currently existing dual-beam laser trapping systems such as small overall dimensions (~15 x 30 x 0 5 mm), low power optical power consumption (<15mW), improved stability of the optical trap due to precise alignment of the optical paths and a relatively easy fabrication process. For these reasons there are many potential applications of the LTM device in biotechnology, microfluidics and other sciences making it an attractive device for commercial use.

Item Type:Thesis (PhD)
Date of Award:2005
Refereed:No
Supervisor(s):MacCraith, Brian
Uncontrolled Keywords:dual-beam optical trapping; Laser Trapping Microchip; LTM
Subjects:Physical Sciences > Physics
Physical Sciences > Lasers
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Physical Sciences
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 License. View License
ID Code:17997
Deposited On:26 Apr 2013 10:32 by Celine Campbell . Last Modified 26 Apr 2013 10:32

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