Local skin chemistry was investigated in human participants using non-invasive approaches to characterise volatile organic compounds, cutaneous pH and tissue dielectric constants (TDC). A total of 26 volatile compounds were identified through headspace solid-phase microextraction sampling with gas chromatography-mass spectrometry analysis. Acids and aldehydes were the predominant volatile species, accompanied by a variety of alcohols, ketones, hydrocarbons and esters. Measured values for pH and TDC were within the normal range for healthy skin. Principle component analysis classified participants into sub-groups, wherein specific volatile markers and skin pH were found to be strongly predictive of participant gender.
Item Type:
Article (Published)
Refereed:
Yes
Uncontrolled Keywords:
Volatile organic compounds; gas chromatography-mass spectrometry; pH; tissue dielectric constant
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Funders:
Horizon 2020 Research and Innovation programme under the Marie Skłodowska-Curie grant agreement number 796289, Science Foundation Ireland grant number 13/CDA/2155
ID Code:
24877
Deposited On:
28 Jul 2020 12:14 by
Emer Duffy
. Last Modified 10 Feb 2022 12:48