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Design and fabrication of a low-cost wireless camera imaging system for centrifugal microfluidics

Regan, Brian orcid logoORCID: 0000-0002-7410-4748, Kinahan, David J. orcid logoORCID: 0000-0003-1968-2016, Daly, Philip, O’Kennedy, Richard and Collins, David (2022) Design and fabrication of a low-cost wireless camera imaging system for centrifugal microfluidics. HardwareX, 11 . ISSN 2468-0672

Centrifugal microfluidic devices offer a robust method for low-volume fluid handling by combining low-cost instrumentation with highly integrated automation. Crucial to the efficacy of Lab-on-a-Disc (LoaD) device operation is the selection of robust valving technology, the design of on-disc fluidic structures, and accurate control of disc spin-speeds (centrifugal force) during operation. The design and refinement of fluidic and valving structures is often guided by inspecting disc operation using high-speed camera systems. This approach involves synchronising image acquisition with disc rotation to visualise liquid flow through a series of images often presented in a video format. Depending on the decisions taken, such systems can cost from €4,000 upwards. This paper outlines the development of a low-cost centrifugal test-stand with an integrated imaging system using a generic wireless camera to record videos directly to a smartphone device. This imaging system can be fabricated using only 3D printers and a low-cost CNC milling machine from widely available materials for approximately €350. High-fidelity imaging of the entire disc for flow visualisation and the recording of real-time colour intensity measurements are facilitated by this standalone device. A vibration analysis study has been performed to determine the rotational velocity range at which the system can be safely operated. Furthermore, the efficacy of the imaging system has been demonstrated by performing real-time colour intensity measurements of dyed water dilutions
Item Type:Article (Published)
Uncontrolled Keywords:Microfluidics; Imaging; Flow visualisation; Lab-on-a-Disc; Real-time measurements
Subjects:Engineering > Mechanical engineering
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Engineering and Computing > School of Mechanical and Manufacturing Engineering
DCU Faculties and Schools > Faculty of Science and Health > School of Biotechnology
Research Institutes and Centres > Advanced Processing Technology Research Centre (APTRC)
Research Institutes and Centres > I-Form
Official URL:https://dx.doi.org/10.1016/j.ohx.2022.e00259
Copyright Information:© 2022 The Authors.
ID Code:27793
Deposited On:27 Sep 2022 10:06 by Thomas Murtagh . Last Modified 24 Mar 2023 10:07

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