Two-photon polymerisation (TPP) is a premier technique that can produce a wide variety of materials applied to chemistry, biology, and medical devices. The production of optics, microcircuits and micro-robots by TPP has also generated interest for its use in material sciences, bacterial sensing, scaffold development, and stem cell research. The majority of devices reported can be functionalised using a variety of chemistries including esterification, amidation, and thiolene-type reactions. However, the use of copper-catalysed azide-alkyne cycloaddition (CuAAC) reactions have not been widely employed. This thesis focuses on the treatment of reactive oxygen species (ROS)-mediated inflammatory conditions, through the development of superoxide dismutase (SOD) mimetic TPP microstructures as medical devices. SOD is a ubiquitous enzyme, responsible for the catalytic redox of superoxide and vital for the viability of the host. Inflammation is a multifaceted and complex response of the body to pathogenic or foreign body invasion, resulting in the up regulation of superoxide as a signalling molecule and antimicrobial factor. Typically, highly regulated inflammatory responses are resolved through set pathways, involving the degradation and removal of pro-inflammatory markers, removal of inflammatory cells, and epithelialisation to return tissues to homeostasis. However, chronic inflammation interventions include non-steroidal anti-inflammatories (NSAIDs) and cyclooxygenase (COX) inhibitors but their use is systemic, non-tissue specific, and can be detrimental to the healing process. In this thesis, SOD mimetic microstructures were designed through the CuAAC conjugation of azide-bearing Cu(II) chelating ligands with alkyne-modified acrylate monomers, which were employed in the development of novel resins. In their Cu(II) chelated state, these ligands act as potent SOD mimetics capable of detoxifying superoxide, a gateway ROS that contributes to chronic and acute inflammatory conditions. A series of micro-medical devices containing these SOD mimetics were printed and their anti-inflammatory properties were evaluated both in-vitro and in-celluo.