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Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection

Vazquez, Mercedes and Benito-Lopez, Fernando and Garcia-Cordero, Jose and Ricco, Antonio and Diamond, Dermot (2009) Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection. In: μTAS 2009 - 13th International Conference of Miniaturized Systems for Chemistry and Life Science, Micro Total Analysis Systems, 1-5 November 2009, Jeju, Korea. ISBN 978-0-9798064-2-1

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Abstract

Detailed information concerning the composition of the raw materials employed in the production of biologics is important for the efficient control and optimization of bioprocesses. We demonstrate the application of electrophoresis microchips with capacitively-coupled contactless conductivity detection (C4D) to the analysis of wa-ter-soluble vitamins and metal cations in raw material solutions that are subse-quently fed into bioreactors for the production of biologics.

Item Type:Conference or Workshop Item (Paper)
Event Type:Conference
Refereed:Yes
Uncontrolled Keywords:electrophoresis microchip; contactless conductivity detection; biopharma raw materials; vitamins; metal cations;
Subjects:Physical Sciences > Analytical chemistry
Biological Sciences > Biochemistry
Engineering > Electronic engineering
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Engineering and Computing > School of Electronic Engineering
DCU Faculties and Schools > Faculty of Science and Health > School of Chemical Sciences
Research Initiatives and Centres > Biomedical Diagnostics Institute (BDI)
Research Initiatives and Centres > Centre for Bioanalytical Science (CBAS)
Research Initiatives and Centres > CLARITY: The Centre for Sensor Web Technologies
Research Initiatives and Centres > National Centre for Sensor Research (NCSR)
Official URL:http://www.microtas2009.org
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:Industrial Development Authority, IDA project #116294, Irish Research Council for Science Engineering and Technology, IRCSET Fellowship No. 2089, Science Foundation Ireland, SFI 05/CE3/B754, Bristol-Myers Squibb
ID Code:15002
Deposited On:08 Apr 2010 12:03 by Fernando Benito-Lopez. Last Modified 26 Apr 2010 11:25

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