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Analysing chem/bio-Markers in saliva using a portable optical detection platform

Coleman, Simon and Kavanagh, Andrew and Orpen, Dylan and Kim, Jung Ho and Lau, King-Tong and Diamond, Dermot (2012) Analysing chem/bio-Markers in saliva using a portable optical detection platform. In: 7th International Workshop in Biosignal Interpretation (BSI 2012), 2-4 July 2012, Palace Hotel, Lake Como, Italy.

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[img]Microsoft PowerPoint (Slides from workshop presentation)


Bipolar Disorder is commonly regulated using a varying dosage of Lithium carbonate and monitored by blood analysis. The proximity of the upper dosage level in blood (1.2mmol), to that of toxicity (>1.5mmol), presents a risk for patient wellbeing from overdose. The infrequency of blood testing creates a potential for overdose to occur between sampling and remain undetected. Additionally, the invasive and often painful nature of frequent blood draws has resulted in the search for alternative non-invasive techniques. One such medium is saliva and we describe the use of simple, well established, optical techniques integrated into a portable wireless device to analyze Chemical and Bio-markers present in this medium. This novel device allows for frequent, real-time monitoring of drug levels (Lithium) and patient psychological state (alpha-amylase) as well as supplementing patient assessments with their Physician and giving the patient a more personalised monitoring of their health during Lithium treatment.

Item Type:Conference or Workshop Item (Invited Talk)
Event Type:Workshop
Subjects:Physical Sciences > Photochemistry
Physical Sciences > Electronic circuits
Physical Sciences > Optoelectronics
Physical Sciences > Chemical detectors
Biological Sciences > Biology
Physical Sciences > Detectors
Physical Sciences > Photonics
Biological Sciences > Biosensors
Physical Sciences > Chemistry
DCU Faculties and Centres:DCU Faculties and Schools > Faculty of Science and Health > School of Chemical Sciences
Research Initiatives and Centres > CLARITY: The Centre for Sensor Web Technologies
Research Initiatives and Centres > National Centre for Sensor Research (NCSR)
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:European Framework Programme 7
ID Code:17115
Deposited On:09 Jul 2012 14:22 by Simon Coleman. Last Modified 01 Feb 2017 14:22

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