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Modification of polymer substrates with extreme ultraviolet — potential application in cancer cell identification

Ahad, Inam Ul ORCID: 0000-0002-3802-6156, Pabijan, J., Pogoda, Katarzyna, Hughes, Cian, Bartnik, Andrejz, Fiedorowicz, Henryk, Lekka, Malgorzata and Brabazon, Dermot ORCID: 0000-0003-3214-6381 (2017) Modification of polymer substrates with extreme ultraviolet — potential application in cancer cell identification. Acta Physica Polonica A, 33 (4). pp. 283-285. ISSN 0587-4246

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Abstract

During the last two decades, the development of laboratory scale extreme ultraviolet sources has been intensified due to growing interest in use of extreme ultraviolet sources photons for various applications in science and technology. In this study, we present a potential application of extreme ultraviolet sources surface modification of polymers to be used as substrates for cancer cell identification. The surface modification of polytetrafluoroethylene (PTFE) polymer samples was performed by a lab scale compact laser-plasma extreme ultraviolet sources source based on a double-stream gas-puff target. The gas target was irradiated with a 3 ns/0.8 J Nd:YAG laser pulse at 10 Hz with 50 and 300 pulses. HCV29 non-malignant transitional epithelium and T24 bladder cells adhesion and proliferation studies on pure and extreme ultraviolet sources modified PTFE surfaces were performed. The extreme ultraviolet sources modified surfaces demonstrated regular increase in cancer cell proliferation comparing to pristine sample. Initial results indicate that extreme ultraviolet sources treated substrates can facilitate the identification of cancer cells

Item Type:Article (Published)
Refereed:Yes
Subjects:Physical Sciences > Detectors
Medical Sciences > Cancer
DCU Faculties and Centres:Research Initiatives and Centres > Advanced Processing Technology Research Centre (APTRC)
DCU Faculties and Schools > Faculty of Engineering and Computing > School of Mechanical and Manufacturing Engineering
Publisher:Polska Akademia Nauk * Instytut Fizyki (Polish Physical Society)
Official URL:https://doi.org/10.12693/APhysPolA.133.283
Copyright Information:© 2018 Polish Physical Society
Use License:This item is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. View License
Funders:EU FP7 Erasmus Mundus Joint Doctorate Programme EXTATIC under framework partnership agreement FPA2012-0033, EU Horizon 2020 research and innovation programme under grant agreement No. 654148 (Laserlab-Europe).
ID Code:22295
Deposited On:26 Mar 2018 14:06 by Thomas Murtagh . Last Modified 20 Sep 2018 13:11

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